
Assistant Professor, Department of Medicine
Contact Information
Patient Care Related:Biosketch
Jacob Baker, MD, PhD is an infectious disease physician. He received his undergraduate degree at Calvin College. He completed his PhD in Microbiology and Molecular Genetics at Michigan State University in the laboratory of Robert Abramovitch, studying the genetics and metabolism of Mycobacterium tuberculosis adaptation to the host environment. He then completed his MD at the Michigan State University College of Human Medicine. He completed his residency in internal medicine and fellowship in infectious disease at Corewell Health Hospitals in Grand Rapids, MI. His clinical and research interests include multidisciplinary sexually transmitted infection screening, coordination of public health efforts with the local health department, and improving outcomes in the treatment of infectious disease.
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Education and Training
- Fellowship 2024, Infectious Disease, Corewell Health West, Michigan State University
- Residency 2022, Internal Medicine, Spectrum Health
- MD 2019, Michigan State University College of Human Medicine
- PhD 2017, Michigan State University
- BS 2011, Calvin College
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Research
- Latent tuberculosis
- Infectious Disease
- HIV/AIDS
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Publications
Williams J.T., Baker J.J., Zheng H., Dechow S.J., Fallon J., Murto M., Albrecht V.J., Gilliland H.N., Olive A.J., Abramovitch R.B. A genetic selection for Mycobacterium smegmatis mutants tolerant to killing by sodium citrate definesa combined role for cation homeostasis and osmotic stress in cell death mSphere. 2023;8(5)
Dechow S.J., Baker J.J., Murto M., Abramovitch R.B. ppe51 Variants Enable Growth of Mycobacterium tuberculosis at Acidic pH by Selectively Promoting Glycerol Uptake Journal of Bacteriology. 2022;204(11)
Baker J.J., Dechow S.J., Abramovitch R.B. Acid Fasting: Modulation of Mycobacterium tuberculosis Metabolism at Acidic pH Trends in Microbiology. 2019;27(11):942-953.
Baker J.J., Abramovitch R.B. Genetic and metabolic regulation of Mycobacterium tuberculosis acid growth arrest Scientific Reports. 2018;8(1)
Baker J.J., Johnson B.K., Abramovitch R.B. Slow growth of Mycobacterium tuberculosis at acidic pH is regulated by phoPR and host-associated carbon sources Molecular Microbiology. 2014;94(1):56-69.
Shen A., Baker J.J., Scott G.L., Davis Y.P., Ho Y.Y., Siliciano R.F. Endothelial cell stimulation overcomes restriction and promotes productive and latent HIV-1 infection of resting CD4+ T cells Journal of Virology. 2013;87(17):9768-9779.
Zhong Z., Baker J., Zylstra-Diegel C., Williams B. Lrp5 and Lrp6 play compensatory roles in mouse intestinal development Journal of Cellular Biochemistry. 2012;113(1):31-38.
Zhong Z., Zylstra-Diegel C.R., Schumacher C.A., Baker J.J., Carpenter A.C., Rao S., Yao W., Guan M., Helms J.A., Lane N.E., Lang R.A., Williams B.O. Wntless functions in mature osteoblasts to regulate bone mass Proceedings of the National Academy of Sciences of the United States of America. 2012;109(33)
Zhou T., Dang Y., Baker J.J., Zhou J., Zheng Y.H. Evidence for Vpr-dependent HIV-1 Replication in Human CD4+ CEM.NKR T-Cells Retrovirology. 2012;9