Clinical Assistant Professor, Department of Surgical Sciences
Biosketch
William Zuke, MD, is an Orthopaedic Surgeon specializing in hip and knee replacement and hip preservation. He graduated from Colorado College with a degree in Biochemistry. He then attended Indiana University School of Medicine where he was inducted into the prestigious Alpha Omega Alpha medical honor society for academic achievement. He completed his residency in Orthopaedic Surgery at the Cleveland Clinic. After residency, he received specialized fellowship training in Joint Preservation, Resurfacing, and Reconstruction at Washington University in St Louis. His fellowship training focused on advanced techniques to preserve the hip joint through arthroscopy and osteotomies in order to delay onset of arthritis. He also developed a strong interest in the incorporation of technology and robotics in the operating room to improve outcomes. He is interested in improving patients' quality of life through treating hip and knee pain with preservation techniques or hip and knee replacements.
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Education and Training
- Fellowship 2024, Joint Preservation, Resurfacing, and Reconstruction, School of Medicine, Washington University in St Louis
- Residency 2023, Orthopaedic Surgery, Department of Orthopaedics, Cleveland Clinic
- MD 2018, Medicine, School of Medicine, Indiana University School of Medicine
- BS 2012, Biochemistry, Colorado College, Colorado College
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Research
- Revision Knee Surgery
- Revision Hip Surgery
- Hip Arthroscopy
- Arthroplasty, Replacement, Knee
- Arthroplasty, Replacement, Hip
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Publications
Gibian J.T., Zuke W.A., Hood H., Blum E., Nunley R.M., Barrack R.L., Bendich I. Early Aseptic Tibial Loosening Is a Concern With a Modern Two-Peg Cementless Total Knee Arthroplasty Design Journal of Arthroplasty. 2025;40:678-682.
Zuke W.A., Hannon C.P., Salih R., Kromka J., Granger C., Clohisy J.C., Barrack R.L. Long-Term Results of the Birmingham Hip Resurfacing Implant in the United States: An Updated Analysis of a Single Institution's Experience Journal of Bone and Joint Surgery. 2025
Grits D., Kim A.G., Zhong J., Chiu A.M., Reading L., Zuke W., Kamath A.F. 5-Factor Modified Frailty Index as a Predictor of Outcomes After Hemiarthroplasty or Total Hip Arthroplasty for Femoral Neck Fracture Journal of the American Academy of Orthopaedic Surgeons. 2024;32(13):e634-e641.
Kim A.G., Rizk A.A., Chiu A.M., Zuke W., Acuña A.J., Kamath A.F. No clinically significant differences in patient-reported outcome measures across total hip arthroplasty approaches HIP International. 2024;34(1):21-32.
Pandey A.K., Zuke W.A., Surace P., Kamath A.F. Management of acetabular bone loss in revision total hip replacement: a narrative literature review Annals of Joint. 2024;9
Joseph N.M., Zuke W., Sharpe M., Bacharach A., Punjabi N., Zhao C., Sattar A., Emara A.K., Piuzzi N.S., Ochenjele G., Patterson B.M., Vallier H.A. Outcomes of Geriatric Periprosthetic Distal Femur Fractures: Comparison of Fixation Versus Reconstruction Journal of Orthopaedic Trauma. 2023;37(10):480-484.
Samuel L.T., Zuke W.A., Mahmood S., Munim M.A., Alamir P.B., Brooks P.J. Hip Resurfacing: A Single Surgeon U.S. Series With Minimum Ten-Year Follow-up Journal of Arthroplasty. 2022;37(9):1799-1808.
Zuke W.A., Chughtai M., Emara A.K., Zhou G., Koroukian S.M., Molloy R.M., Piuzzi N.S. What Are Drivers of Readmission for Readmission-Requiring Venous Thromboembolic Events After Primary Total Hip Arthroplasty? An Analysis of 544,443 Cases Journal of Arthroplasty. 2022;37(5):958-965.e3.
Forsythe B., Zuke W.A., Agarwalla A., Puzzitiello R.N., Garcia G.H., Cvetanovich G.L., Yanke A.B., Verma N.N., Romeo A.A. Arthroscopic Suprapectoral and Open Subpectoral Biceps Tenodeses Produce Similar Outcomes: A Randomized Prospective Analysis Arthroscopy - Journal of Arthroscopic and Related Surgery. 2020;36(1):23-32.
Puzzitiello R.N., Waterman B., Agarwalla A., Zuke W., Cole B.J., Verma N.N., Yanke A.B., Forsythe B. Primary Medial Patellofemoral Ligament Repair Versus Reconstruction: Rates and Risk Factors for Instability Recurrence in a Young, Active Patient Population Arthroscopy - Journal of Arthroscopic and Related Surgery. 2019;35(10):2909-2915.
Weber A.E., Zuke W., Mayer E.N., Forsythe B., Getgood A., Verma N.N., Bach B.R., Bedi A., Cole B.J. Lateral Augmentation Procedures in Anterior Cruciate Ligament Reconstruction: Anatomic, Biomechanical, Imaging, and Clinical Evidence American Journal of Sports Medicine. 2019;47(3):740-752.
Forsythe B., Lansdown D., Zuke W.A., Verma N.N., Cole B.J., Bach B.R., Inoue N. Dynamic 3-Dimensional Mapping of Isometric Anterior Cruciate Ligament Attachment Sites on the Tibia and Femur: Is Anatomic Also Isometric? Arthroscopy - Journal of Arthroscopic and Related Surgery. 2018;34(8):2466-2475.
Forsythe B., Zuke W., Puzzitiello R., Romeo A. Arthroscopic Suprapectoral Biceps Tenodesis With Tenodesis Screw Arthroscopy Techniques. 2018;7(5):e417-e422.
Leroux T.S., Zuke W.A., Saltzman B.M., Go B., Verma N.N., Romeo A.A., Hurst J., Forsythe B. Safety and patient satisfaction of outpatient shoulder arthroplasty JSES Open Access. 2018;2(1):13-17.
Mellano C.R., Frank R.M., Shin J.J., Jain A., Zuke W.A., Mascarenhas R., Shewman E., Cole B.J., Romeo A.A., Verma N.N., Forsythe B. Subpectoral Biceps Tenodesis With PEEK Interference Screw: A Biomechanical Analysis of Humeral Fracture Risk Arthroscopy - Journal of Arthroscopic and Related Surgery. 2018;34(3):806-813.
Puzzitiello R., Agarwalla A., Zuke W., Garcia G., Forsythe B. Imaging Diagnosis of Injury to the Anterolateral Ligament in Patients With Anterior Cruciate Ligaments: Association of Anterolateral Ligament Injury With Other Types of Knee Pathology and Grade of Pivot-Shift Examination: A Systematic Review Arthroscopy - Journal of Arthroscopic and Related Surgery. 2018;34(9):2728-2738.
Zuke W.A., Agarwalla A., Go B., Griffin J.W., Cole B.J., Verma N.N., Bach B.R., Forsythe B. The lack of standardized outcome measures following lower extremity injury in elite soccer: a systematic review Knee Surgery, Sports Traumatology, Arthroscopy. 2018;26(10):3109-3117.
Zuke W.A., Leroux T.S., Gregory B.P., Black A., Forsythe B., Romeo A.A., Verma N.N. Establishing Maximal Medical Improvement After Arthroscopic Rotator Cuff Repair American Journal of Sports Medicine. 2018;46(4):1000-1007.
Forsythe B., Collins M.J., Arns T.A., Zuke W.A., Khair M., Verma N.N., Cole B.J., Bach B.R., Inoue N. Optimization of Anteromedial Portal Femoral Tunnel Drilling With Flexible and Straight Reamers in Anterior Cruciate Ligament Reconstruction: A Cadaveric 3-Dimensional Computed Tomography Analysis Arthroscopy - Journal of Arthroscopic and Related Surgery. 2017;33(5):1036-1043.
Makhni E.C., Stone A.V., Ukwuani G.C., Zuke W., Garabekyan T., Mei-Dan O., Nho S.J. A Critical Review: Management and Surgical Options for Articular Defects in the Hip Clinics in Sports Medicine. 2017;36(3):573-586.
Rao A., Cvetanovich G., Zuke W., Go B., Forsythe B. Single-Bundle Augmentation for a Partial Tear of the Anterior Cruciate Ligament Arthroscopy Techniques. 2017;6(3):e853-e857.
Rao A., Cvetanovich G., Zuke W., Low Q., Forsythe B. Arthroscopic Repair of a Circumferential 360° Labral Tear Arthroscopy Techniques. 2017;6(4):e1131-e1136.
Saltzman B.M., Zuke W.A., Go B., Mascarenhas R., Verma N.N., Cole B.J., Romeo A.A., Forsythe B. Does early motion lead to a higher failure rate or better outcomes after arthroscopic rotator cuff repair? A systematic review of overlapping meta-analyses Journal of Shoulder and Elbow Surgery. 2017;26(9):1681-1691.
Zuke W.A., Cvetanovich G.L., Go B., Forsythe B. Arthroscopic Saucerization and All-Inside Repair of a Delaminated Discoid Lateral Meniscus Arthroscopy Techniques. 2017;6(4):e1387-e1391.
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Presentations
- The New 5-Factor Modified Frailty Index Predicts Morbidity in Femoral Neck Fracture Patients. . Kim AG, Grits D, Zhong J, Chiu AM, Zuke WA, Karnath AF, American Association of Hip and Knee Surgeons Annual Meeting, Grapevine, TX, 11/2023
- Hip Resurfacing through a Direct Lateral Approach. Zuke, WA, Brooks, PJ., American Academy of Orthopaedic Surgeons Annual Meeting, Las Vegas, NV, 03/2023
- What Are Drivers of Readmission for Readmission-Requiring Venous Thromboembolic Events After Primary Total Hip Arthroplasty? An Analysis of 544,443 Cases.. Zuke WA, Chughtai M, Emara AK, Zhou G, Koroukian SM, Molloy RM, Piuzzi NS, American Academy of Orthopaedic Surgeons Annual Meeting, Chicago, IL, 03/2022
- Risk factors for readmission and complications within thirty days of total shoulder arthroplasty. Inconsistencies within the NSQIP database. Zuke, WA; Forsythe, B, Ohio Shoulder and Elbow Society Annual Meeting, New Albany, OH, 01/2019
- Dynamic 3D Mapping of the Isometric Anterior Cruciate Ligament Attachment Sites on the Tibia and Femur. Forsythe, B; Zuke, WA; Lansdown, DA; Verma, NN; Cole, BJ; Bach, BR; Nozomu, I, American Academy of Orthopaedic Surgeons Annual Meeting, New Orleans, LA, 03/2018
- Safety and Patient Satisfaction of Outpatient Shoulder Arthroplasty. Leroux, TS; Zuke, WA; Saltzman, BM; Verma, NN; Romeo, AA; Hurst, J; Forsythe, B, American Shoulder and Elbow Surgeons Annual Closed Meeting, New Orleans, LA, 10/2017
- Establishing Maximal Medical Improvement in Arthroscopic Rotator Cuff Repairs. Zuke, WA; Leroux, TS; Gregory, B; Black, A; Forsythe, B; Romeo, A.A., Verma, NN, European Society for Surgery of the Shoulder and Elbow (ESSSE) Congress, Berlin, Germany, 09/2017
- Establishing Maximal Medical Improvement in Arthroscopic Rotator Cuff Repairs. Leroux, TS; Zuke, WA; Gregory, B; Black, A; Forsythe, B; Romeo, AA; Cole, BJ; Verma, NN, American Orthopaedic Society for Sports Medicine annual meeting, Toronto, Canada, 07/2017
- Randomized Prospective Analysis of Arthroscopic Suprapectoral and Open Subpectoral Biceps Tenodesis: 1 Year Follow Up. Forsythe, B; Zuke, WA; Go, B; Yanke, AB; Verma, NN; Romeo, AA, American Orthopaedic Society for Sports Medicine Annual Meeting, Toronto, Canada, 07/2017
- A Multicenter Study Investigating Factors that Influence Initiation of Return to Sport Functional Testing Following ACL Reconstruction. Sherman, SL; Zuke WA; Go, B; Thyssen, E; Cvetanovich, GL; Hannafin, JA; Forsythe, B. A, International Society of Arthroscopy, Knee Surgery, and Orthopaedic Sports Medicine annual meeting, Shanghai, China, 06/2017
- Randomized Prospective Analysis of Arthroscopic Suprapectoral and Open Subpectoral Biceps Tenodesis: 1 Year FollowÂUp. Forsythe, B; Zuke, WA; Go, B; Yanke, AB; Verma, NN; Romeo, AA, International Society of Arthroscopy, Knee Surgery, and Orthopaedic Sports Medicine annual meeting, Shanghai, China, 06/2017
- Establishing Maximal Medical Improvement in Arthroscopic Rotator Cuff Repairs.. Leroux, TS; Zuke, WA; Gregory, B; Black, A; Forsythe, B; Romeo, AA; Cole, BJ; Verma, NN, Arthroscopy Association of North America annual meeting, Denver, CO, 05/2017
- Randomized Prospective Analysis of Arthroscopic Suprapectoral and Open Subpectoral Biceps Tenodesis: 1 Year FollowÂUp.. Forsythe, B; Zuke, WA; Go, B; Yanke, AB; Verma, NN; Romeo, AA, Arthroscopy Association of North America annual meeting, Denver, CO, 05/2017
- Dynamic 3D Mapping of the Isometric Anterior Cruciate Ligament Attachment Sites on the Tibia and Femur. Forsythe, B; Zuke, WA; Go, B; Verma, NN; Cole, BJ; Bach, BR; Nozomu, I, Arthroscopy Association of North America annual meeting,, Denver, CO, 05/2017
- Lateral-Based Soft Tissue Augmentation in ACL Reconstruction: Historical Perspectives, Biomechanical Evidence, and Clinical Outcomes. Weber, AE; Zuke, WA; Leroux, TS; Forsythe, B; Verma, NN; Getgood, A; Claes, S; Bach, BR; Cole, BJ; Bedi, A, American Academy of Orthopaedic Surgeons annual meeting, San Diego, CA, 03/2017