Assistant Professor, Department of Pediatric and Adolescent Medicine
Contact InformationPatient Care Related:
Steven Proper, DO, PhD, is a board-certified allergist and immunologist. He received his undergraduate degree at Kettering University (Environmental Chemistry, 2005) before completing the DO-PhD Program at Michigan State University in 2015. His PhD thesis was investigating the role of hypoxia signaling (hypoxia-inducible factors or HIFs) in cobalt toxicity and development of lung epithelium. He then completed a pediatrics residency at the Medical College of Wisconsin (Milwaukee, 2018), followed by a clinical fellowship in Allergy and Immunology at Cincinnati Children's Hospital Medical Center (2020). He then completed an Advanced Allergy and Immunology Research Training Fellowship at Cincinnati Children's (2022) prior to his appointment as Assistant Professor of Pediatrics and Adolescent Medicine at the Western Michigan University Homer Stryker M.D. School of Medicine. Dr. Proper's primary clinical interests include allergy and immunology, especially asthma care, oral immunotherapy for food allergy, atopic dermatitis (eczema), hereditary angioedema and immune deficiency. He enjoys teaching all levels of trainees and is interested in pursuing clinical outcomes-based research in allergy and immunology.
Education and Training
- Advanced Fellowship 2022, Allergy and Immunology Research Training Fellowship, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center
- Fellowship 2020, Allergy and Immunology, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center
- Residency 2018, Pediatrics, Medical College of Wisconsin
- DO 2015, Osteopathic Medicine, Michigan State University College of Osteopathic Medicine
- PhD 2013, Biochemistry and Molecular Biology, Environmental Toxicology, College of Natural Sciences, Michigan State University
- BS 2005, Environmental Chemistry, College of Natural Sciences, Kettering University
- Primary Immune Deficiency
- Pediatric Allergy and Immunology
- Oral Immunotherapy
- Hereditary Angioedema
- Food Allergy
- Dermatitis, Atopic
- Asthma Management
Mersha T.B., Afanador Y., Johansson E., Proper S.P., Bernstein J.A., Rothenberg M.E., Khurana Hershey G.K. Resolving Clinical Phenotypes into Endotypes in Allergy: Molecular and Omics Approaches Clinical Reviews in Allergy and Immunology. 2021;60(2):200-219.
Proper S.P., Azouz N.P., Mersha T.B. Achieving Precision Medicine in Allergic Disease: Progress and Challenges Frontiers in Immunology. 2021;12
Proper S.P., Lavery W.J., Bernstein J.A. Definition and classification of hereditary angioedema Allergy and Asthma Proceedings. 2020;41(6):S3-S7.
Saini Y., Proper S., Dornbos P., Greenwood K., Kopec A., Lynn S., Grier E., Burgoon L., Zacharewski T., Thomas R., Harkema J., LaPres J. Loss of Hif-2α rescues the Hif-1α deletion phenotype of neonatal respiratory distress in mice PLoS ONE. 2015;10(9)
Proper S., Saini Y., Greenwood K., Bramble L., Downing N., Harkema J., LaPres J. Loss of hypoxia-inducible factor 2 alpha in the lung alveolar epithelium of mice leads to enhanced eosinophilic inflammation in cobalt-induced lung injury Toxicological Sciences. 2014;137(2):447-457.
Greenwood K., Proper S., Saini Y., Bramble L., Jackson-Humbles D., Wagner J., Harkema J., LaPres J. Neonatal epithelial hypoxia inducible factor-1α expression regulates the response of the lung to experimental asthma American Journal of Physiology - Lung Cellular and Molecular Physiology. 2012;302(5)
Ham J.E., Proper S.P., Wells J. Gas-phase chemistry of citronellol with ozone and OH radical: Rate constants and products Atmospheric Environment. 2006;40(4):726-735.