Professor Emeritus, Department of Biomedical Sciences
Contact Information
Email:Biosketch
Dale Vandré, PhD, is the former Associate Dean for Research at Western Michigan University Homer Stryker M.D. School of Medicine, as well as Chair and Professor of the Department of Biomedical Sciences. He retired in 2020. He is a graduate of University of Arizona in Tucson, Arizona. He earned his doctorate in biochemistry from University of Iowa in Iowa City, Iowa.
Dr. Vandré came to WMed from Ohio State University's College of Medicine, where he served as the vice chair of the physiology and cell biology department, assistant dean for foundational science, and director of the integrated pathway program.
A biochemist and cell biologist, Dr. Vandré earned his PhD from the University of Iowa. He was an active researcher in the cellular and molecular biology of cancer, with consistent research funding from the National Institutes of Health and the National Science Foundation.
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Education and Training
- PhD 1980, Biochemistry, University of Iowa
- BS 1976, Microbiology, University of Arizona
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Research
- Biochemistry
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Publications
Sheakley M.L., Bauler T.J., Vandre D.D., Woodwyk A., Dickinson B.L. Effectiveness of instructor-guided independent learning in comparison to traditional didactic lecture in the preclinical medical curriculum: A retrospective cohort study Medical Teacher. 2019;41(7):795-801.
Keator C., Dickinson B.L., Lackey W.L., Morris A., Quesnelle K.M., Riddle D.R., Sheakley M.L., Vanden Heuvel G.B., Vandre D.D. Explorations: a New Approach to Self-Directed Learning in a Competency-Based Curriculum Medical Science Educator. 2016;26:777-785.
Keator C., Vandre D.D., Morris A.M. The Challenges of Developing a Project-Based Self-Directed Learning Component for Undergraduate Medical Education Medical Science Educator. 2016;26:801-805.
Gonzalez I.M., Ackerman W.E., Vandre D.D., Robinson J.M. Exocyst complex protein expression in the human placenta Placenta. 2014;35:442-449.
Ishikawa A., Omata W., Ackerman W.E., Takeshita T., Vandré D.D., Robinson J.M. Cell fusion mediates dramatic alterations in the actin cytoskeleton, focal adhesions, and E-cadherin in trophoblastic cells Cytoskeleton. 2014;71:241-256.
Martin S.I., Way D.P., Verbeck N., Nagel R., Davis J.A., Vandre D.D. The impact of lecture attendance and other variables on how medical students evaluate faculty in a preclinical program Academic Medicine. 2013;88:972-977.
Omata W., Ackerman IV W.E., Vandre D.D., Robinson J.M. Trophoblast cell fusion and differentiation are mediated by both the protein kinase C and A pathways PLoS ONE. 2013;8
Walton J.R., Frey H.A., Vandre D.D., Kwiek J.J., Ishikawa T., Takizawa T., Robinson J.M., Ackerman W.E. Expression of flotillins in the human placenta: Potential implications for placental transcytosis Histochemistry and Cell Biology. 2013;139:487-500.
Vandré D.D., Ackerman IV W.E., Tewari A., Kniss D.A., Robinson J.M. A placental sub-proteome: The apical plasma membrane of the syncytiotrophoblast Placenta. 2012;33:207-213.
Alcamo A.M., Davids A., Way D.P., Lynn D.J., Vandre D.D. The impact of a peer-designed and -led USMLE step 1 review course: Improvement in preparation and scores Academic Medicine. 2010;85
Lang C.T., Markham K.B., Behrendt N., Suarez A.A., Samuels P., Vandre D.D., Robinson J.M., Ackerman IV W.E. Placental Dysferlin Expression is Reduced in Severe Preeclampsia Placenta. 2009;30:711-718.
Robinson J., Vandré D., Ackerman IV W. Placental Proteomics: A Shortcut to Biological Insight Placenta. 2009;30:83-89.
Robinson J.M., Ackerman IV W.E., Behrendt N., Vandre D.D. While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems Biology of Reproduction. 2009;81:33-39.
Robinson J.M., Ackerman IV W.E., Tewari A.K., Kniss D.A., Vandre D.D. Isolation of highly enriched apical plasma membranes of the placental syncytiotrophoblast Analytical Biochemistry. 2009;387:87-94.
Ackerman IV W.E., Summerfield T.L.S., Vandre D.D., Robinson J.M., Kniss D.A. Nuclear factor-kappa B regulates inducible prostaglandin E synthase expression in human amnion mesenchymal cells Biology of Reproduction. 2008;78:68-76.
Robinson J.M., Ackerman IV W.E., Kniss D.A., Takizawa T., Vandré D.D. Proteomics of the Human Placenta: Promises and Realities Placenta. 2008;29:135-143.
Vandré D.D., Ackerman IV W.E., Kniss D.A., Tewari A.K., Mori M., Takizawa T., Robinson J.M. Dysferlin is expressed in human placenta but does not associate with caveolin Biology of Reproduction. 2007;77:533-542.
Kannanayakal T., Tao H., Vandre D., Kuret J. Casein kinase-1 isoforms differentially associate with neurofibrillary and granulovacuolar degeneration lesions Acta Neuropathologica. 2006;111:413-421.
Marsee D., Venkateswaran A., Tao H., Vadysirisack D., Zhang Z., Vandre D.D., Jhiang S.M. Inhibition of heat shock protein 90, a novel RET/PTC1-associated protein, increases radioiodide accumulation in thyroid cells Journal of Biological Chemistry. 2004;279:43990-43997.
Robinson J.M., Takizawa T., Vandré D.D. Gold cluster immunoprobes: Light and electron microscopy Gold and Silver Staining: Techniques in Molecular Morphology. 2002:177-187.
Thomas J., Moore T., Kraut E., Balcerzak S., Galloway S., Vandre D. A phase II study of CI-980 in previously untreated extensive small cell lung cancer: An Ohio State University Phase II Research Consortium study Cancer Investigation. 2002;20:192-198.
Brueggemeier R.W., Bhat A.S., Lovely C.J., Coughenour H.D., Joomprabutra S., Weitzel D., Vandre D.D., Yusuf F., Burak W.E. 2-Methoxymethylestradiol: A new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics Journal of Steroid Biochemistry and Molecular Biology. 2001;78:145-156.
Robinson J.M., Vandré D.D. Antigen retrieval in cells and tissues: Enhancement with sodium dodecyl sulfate Histochemistry and Cell Biology. 2001;116:119-130.
Robinson J.M., Takizawa T., Vandré D.D. Applications of gold cluster compounds in immunochemistry and correlative microscopy: Comparison with colloidal gold Journal of Microscopy. 2000;199:163-179.
Robinson J.M., Takizawa T., Vandré D.D. Enhanced labeling efficiency using ultrasmall immunogold probes: Immunocytochemistry Journal of Histochemistry and Cytochemistry. 2000;48:487-492.
Vandré D.D., Feng Y., Ding M. Cell cycle-dependent phosphorylation of centrosomes: Localization of phosphopeptide specific antibodies to the centrosome Microscopy Research and Technique. 2000;49:458-466.
Weitzel D., Vandré D.D. Differential spindle assembly checkpoint response in human lung adenocarcinoma cells Cell and Tissue Research. 2000;300:57-65.
Robinson J.M., Takizawa T., Vandré D.D., Burry R.W. Ultrasmall immunogold particles: Important probes for immunocytochemistry Microscopy Research and Technique. 1998;42:13-23.
Robinson J.M., Vandre D.D. Neutrophil Microtubules Display Unusual Properties and are Highly Sensitive to Taxol Microscopy and Microanalysis. 1998;4:1038-1039.
Ding M., Feng Y., Vandré D.D. Partial characterization of the MPM-2 phosphoepitope Experimental Cell Research. 1997;231:3-13.
Robinson J.M., Vandré D.D. Efficient immunocytochemical labeling of leukocyte microtubules with FluoroNanogold: An important tool for correlative microscopy Journal of Histochemistry and Cytochemistry. 1997;45:631-642.
Ding M., Vandré D.D. High molecular weight microtubule-associated proteins contain O-linked N-acetylglucosamine Journal of Biological Chemistry. 1996;271:12555-12561.
Kondratick C., Vandré D.D. Alzheimer's disease neurofibrillary tangles contain mitosis-specific phosphoepitopes Journal of Neurochemistry. 1996;67:2405-2416.
Ding M., Robinson J.M., Behrens B., Vandre D.D. The microtubule cytoskeleton in human phagocytic leukocytes is a highly dynamic structure European Journal of Cell Biology. 1995;66:234-245.
Robinson J.M., Vandré D.D. Stimulus-dependent alterations in macrophage microtubules: Increased tubulin polymerization and detyrosination Journal of Cell Science. 1995;108:645-655.
Burry R., Vandre D., Hayes D. Silver enhancement of gold antibody probes in pre-embedding electron microscopic immunocytochemistry Journal of Histochemistry and Cytochemistry. 1992;40:1849-1856.
Chiplonkar J.M., Vandré D.D., Robinson J.M. Stimulus-dependent relocation of the microtubule organizing center in human polymorphonuclear leukocytes Journal of Cell Science. 1992;102:723-728.
Vandre D., Burry R. Immunoelectron microscopic localization of phosphoproteins associated with the mitotic spindle Journal of Histochemistry and Cytochemistry. 1992;40:1837-1847.
Vandré D.D., Wills V.L. Inhibition of mitosis by okadaic acid: Possible involvement of a protein phosphatase 2A in the transition from metaphase to anaphase Journal of Cell Science. 1992;101:79-91.
Vandré D.D., Centonze V.E., Peloquin J., Tombes R.M., Borisy G.G. Proteins of the mammalian mitotic spindle: Phosphorylation/dephosphorylation of MAP-4 during mitosis Journal of Cell Science. 1991;98:577-588.
Riabowol K., Draetta G., Brizuela L., Vandre D., Beach D. The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells Cell. 1989;57:393-401.
Vandre D., Borisy G. Anaphase onset and dephosphorylation of mitotic phosphoproteins occur concomitantly Journal of Cell Science. 1989;94:245-258.
Iyer S., Zaheer S., Vandré D., Long C., Montgomery R. Characterization of human interferon species using gel extraction and monoclonal antibodies: implications on clinical use of interferon preparations Journal of Biological Response Modifiers. 1986;5:548-561.
Vandré D., Davis F., Rao P., Borisy G. Distribution of cytoskeletal proteins sharing a conserved phosphorylated epitope. European Journal of Cell Biology. 1986;41:72-81.
Vandre D., Davis F., Rao P., Borisy G. Phosphoproteins are components of mitotic microtubule organizing centers Proceedings of the National Academy of Sciences of the United States of America. 1984;81:4439-4443.
Vandré D.D., Montgomery R. Antitumor Proteins of Streptomyces macromomyceticus: Purification and Characterization of Auromomycin, Macromomycin A, and Macromomycin D Biochemistry. 1982;21:3343-3352.
Vandré D.D., Zaheer A., Squier S., Montgomery R. Largomycin: Preparation, Properties, and Structure Biochemistry. 1982;21:5089-5096.
Shepherd V.L., Vandré D.D., Elting J., Montgomery R. Effects of cesalin on the ultrastructure and biological properties of cultured mammalian cells Cancer Research. 1980;40:225-231.
Vandre D., Shepherd V., Montgomery R. Effects of Macromomycin on the Ultrastructure and Biological Properties of Cultured Mammalian Cells Cancer Research. 1979;39:4091-4097.
Vandré D., Montgomery R. Strand scission of DNA in KB cells by macromomycin Archives of Biochemistry and Biophysics. 1979;193:560-563.
Bin Im W., Chiang C., Vandre D., Montgomery R. Macromomycin an anti tumor protein Federation Proceedings. 1977;36